Multiplex genotyping using fluorescent hybridization probes
US6140054A · kind A · utility
178Cited by
4References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 30, 1998 |
| Grant date | Oct 31, 2000 |
| Priority date | — |
| Expiry date | Sep 30, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/686
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention is directed to a mutation detection kit and method of analyzing multiple loci of one or more nucleic acid sequences for the presence of mutations or polymorphisms. More particularly, the present invention relates to the use of the polymerase chain reaction (PCR) and fluorescently labeled oligonucleotide hybridization probes to identify mutations and polymorphisms based on melting curve analysis of the hybridization probes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.