Phosphorous prodrugs
US6140310A · kind A · utility
29Cited by
7References
5Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | May 6, 1998 |
| Grant date | Oct 31, 2000 |
| Priority date | — |
| Expiry date | May 6, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/20
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The composition and methods of synthesis of phosphorus prodrugs are described. These methods can be used to convert negatively charged phosphorus bearing drugs into neutrally charged; lipid soluble prodrugs which are able to passively diffuse into cells and into tissues in vivo. Prodrugs for a variety of antiviral and anti-leukemic agents are described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.