Morpholino-n-ethyl ester derivative of an indole sPLA.sub.2 inhibitor
US6140327A · kind A · utility
1Cited by
1References
5Claims
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Key dates
| Filing date | May 12, 1999 |
| Grant date | Oct 31, 2000 |
| Priority date | — |
| Expiry date | May 12, 2019 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The compound, ((3-(2-amino-1,2-dioxoethyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl)oxy)ac etic acid morpholino-N-ethyl ester, is disclosed together with its use as a highly bioavailable indole compound for inhibiting sPLA.sub.2 mediated release of fatty acids for treatment of conditions such as septic shock.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.