Therapeutic composition containing antibodies to soluble polypeptide fractions of LAG-3 protein
US6143273A · kind A · utility
60Cited by
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5Claims
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Key dates
| Filing date | Apr 13, 1998 |
| Grant date | Nov 7, 2000 |
| Priority date | — |
| Expiry date | Apr 13, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Soluble polypeptide fraction consisting of all or part of one at least one of the four immunoglobulin-type extracellular LAG-3 protein domains (amino acids 1-159, 160-230, 240-330 and 331-412 of the SEQ ID NO:1 sequence) or consisting of one peptide sequence derived from these domains by replacement, addition or deletion of one or more amino acids. The fraction of the invention has a specificity at least equal to that of LAG-3 in relation to its ligand.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.