High throughput compatible assay for receptor-TRAF interactions
US6143507A · kind A · utility
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7Claims
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Key dates
| Filing date | Oct 29, 1998 |
| Grant date | Nov 7, 2000 |
| Priority date | — |
| Expiry date | Oct 29, 2018 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/866
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed is a high throughput compatible assay that is useful for the identification of specific antagonists of TRAF-receptor interactions. The modular flexibility of the assay makes it possible to introduce simple modifications in order to measure the interaction of any TNF receptor cytoplasmic domain (or TRAF-binding protein) with any of the six TRAF proteins, TRAF1, TRAF2, TRAF3, TRAF4, TRAF5 and TRAF6.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.