Patent · US Expired

Peptides

US6143864A · kind A · utility

26Cited by
16References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 6, 1995
Grant dateNov 7, 2000
Priority date
Expiry dateJun 6, 2015

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Oligopeptides which comprise amino acid sequences that are recognized and proteolytically cleaved by free prostate specific antigen (PSA) are described. Also described are assays which comprise such oligopeptides useful for determining free PSA protease activity in vitro and in vivo. Therapeutic agents which comprise conjugates of such oligopeptides and known cytotoxic agents are also described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.