Patent · US Expired

Preparation of beta-methyl carbapenem intermediates

US6143885A · kind A · utility

16Cited by
7References
26Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 28, 1998
Grant dateNov 7, 2000
Priority date
Expiry dateJul 28, 2018

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02P20/55
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The instant invention relates to a compound of the formula: ##STR1## wherein R.sub.a and P are: (a) hydrogen, PA1 (b) methyl, or PA1 (c) a hydroxy protecting group and an efficient process for its synthesis characterized by combining a ketoester with an acid and a catalyst at a temperature of from about 0.degree. to about 50.degree. C. and from about 0 to 500 psig to produce the above compound.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.