Patent · US Expired

Biotherapeutic agents comprising recombinant PAP and PAP mutants

US6146628A · kind A · utility

11Cited by
7References
12Claims
0Family size

Assignees

Inventors

Key dates

Filing dateJul 11, 1995
Grant dateNov 14, 2000
Priority date
Expiry dateJul 11, 2015

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2317/74
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Biotherapeutic agents are provided which comprise recombinant PAP or a biologically equivalent variant or mutant thereof, linked to a targeting moiety which are effective for the treatment of certain human diseases. The invention further provides a process for producing the biotherapeutic agents as well as a method which utilizes the disclosed biotherapeutic agents to systemically treat cancer patients.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.