Patent · US Expired

Production of orthomyxoviruses in monkey kidney cells using protein-free media

US6146873A · kind A · utility

88Cited by

11References

37Claims

0Family size

Assignee

Baxter Aktiengesellschaft · AT

Inventors

Otfried Kistner · Wien, AT
Noel Barrett · Klosterneuburg, AT
Wofgang Mundt · Wien, AT
Friedrich Dorner · Wien, AT

Key dates

Filing date	Oct 15, 1997
Grant date	Nov 14, 2000
Priority date	—
Expiry date	Oct 15, 2017

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2770/24151
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Viruses from the family Orthomyxoviridae, particularly influenza virus, can grown in monkey kidney cells, particularly Vero Cells, after passaging the cells in a serum-free or protein-free medium. The use of a proteolytic enzyme, especially trypsin, also aids in the propagation of the virus. The method allows for the virus to be produced to be used in a vaccine.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.