Azospiro compounds as NK1 or NK2 antagonists
US6147083A · kind A · utility
18Cited by
23References
12Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Aug 27, 1999 |
| Grant date | Nov 14, 2000 |
| Priority date | — |
| Expiry date | Aug 27, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D495/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of formula I: ##STR1## wherein Q.sup.1, Q.sup.2, Q.sup.3, Q.sup.4, and Q.sup.5 have any of the meanings given in the specification, their N-oxides, and their pharmaceutically acceptable salts are nonpeptide antagonists of SP and NKA are useful for the treatment of asthma, etc. Also disclosed are pharmaceutical compositions, processes for preparing the compounds of formula I and intermediates.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.