Local delivery of estrogen for angiogenesis
US6149641A · kind A · utility
60Cited by
24References
11Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Dec 23, 1998 |
| Grant date | Nov 21, 2000 |
| Priority date | — |
| Expiry date | Dec 23, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2300/412
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for inducing angiogenesis in blood vessels proximal to ischemic tissue or proximal to stenosed regions including application of an estrogen compound to the blood vessel walls at a treatment site proximal to or upstream of the stenosis. A preferred delivery device is a double walled drug delivery catheter having porous outer walls. Another suitable delivery device is a drug injection device for injecting angiogenic material into blood vessel walls. One delivery method utilizes iontophoresis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.