Peptides for the detection of HIV-1 group O
US6149910A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 4, 1999 |
| Grant date | Nov 21, 2000 |
| Priority date | — |
| Expiry date | Nov 4, 2019 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/162
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
This invention relates to peptides and their preparation. The peptides each have a sequence that corresponds to the immunodominant region of the HIV-1 group O gp41 envelope protein. The sequence is characterized in that it does not correspond to any known naturally occurring group O sequence or variant. Furthermore, the peptide binds anti-HIV-1 group O antibodies. There are several uses for the peptides, including the detection of antibodies produced in response to HIV-1 group O infection. The peptides may also be incorporated in mosaics and expressed recombinantly.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.