Vaccine compositions for eliciting an immune response against N-acetylated gangliosides and their use for cancer treatment
US6149921A · kind A · utility
8Cited by
6References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 17, 1998 |
| Grant date | Nov 21, 2000 |
| Priority date | — |
| Expiry date | Apr 17, 2018 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/828
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides novel uses for n-glycolylated gangliosides and N-acetylated gangliosides, or derivatives and/or oligosaccharides thereof The invention further provides methods of obtaining such gangliosides, as well as vaccine compositions comprising said gangliosides. The gangliosides may be coupled to carriers and may be accompanied by adjuvants. The vaccine compositions can be used in the treatment of breast cancers, whereby the gangliosides are used to elicit an immune response to corresponding gangliosides on breast tumor cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.