HMGI(Y)-LAMA4* fusion oncogene, oncoprotein and methods of use
US6150110A · kind A · utility
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Key dates
| Filing date | Feb 26, 1999 |
| Grant date | Nov 21, 2000 |
| Priority date | — |
| Expiry date | Feb 26, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/158
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
An oncogene designated HMGI(Y)-LAMA4* incorporates a HMGI(Y) domain fused through inversion and translocation to LAMA4*, a novel gene transcript with a epidermal-growth-factor-like/zinc-finger-like motif. Molecular characterization of HMGI(Y)-LAMA4* provides nucleic acid sequences and amino acid sequences useful for detection and treatment of certain tumors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.