Assessing immunological state of transplant recipients
US6150121A · kind A · utility
19Cited by
7References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 16, 1999 |
| Grant date | Nov 21, 2000 |
| Priority date | — |
| Expiry date | Feb 16, 2019 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/55
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed herein are methods for monitoring the immunological status of transplant recipients. Fibroblast cells derived from transplanted organs are used in proliferation assays with lymphocytes taken from the recipient after transplantation. The comparison of assay results in the presence of, and in the absence of (or in the presence of reduced levels of) a cytokine growth factor such as interleukin-2, is used to determine whether the organ is being rejected. Also disclosed are kits for practicing these methods.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.