Antagonists of gonadotropin releasing hormone

US6150352A · kind A · utility

Assignee

• MERCK & CO., INC. · US

Inventors

• Mark Goulet · Westfield, US
• Eric E. Allen · Somerville, US
• Matthew J. Wyvratt · Mountainside, US
• Jinlong Jiang · Scotch Plains, US
• Richard B. Toupence · West Milford, US
• Thomas F. Walsh · Stoneham, US
• Feroze Ujjainwalla · Hoboken, US
• Jonathan R. Young · Southborough, US
• Robert J. DeVita · Westfield, US

Key dates

• Filing date: Nov 12, 1998
• Grant date: Nov 21, 2000
• Expiry date: Nov 12, 2018

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D495/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

There are disclosed compounds of formula (I) ##STR1## and pharmaceutically acceptable salts thereof which are useful as antagonists of GnRH and as such may be useful for the treatment of a variety of sex-hormone related conditions in both men and women.