Small molecule modulators of non-endogenous, constitutively activated human serotonin receptors
US6150393A · kind A · utility
82Cited by
2References
12Claims
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Assignee
Inventors
Key dates
| Filing date | Oct 15, 1999 |
| Grant date | Nov 21, 2000 |
| Priority date | — |
| Expiry date | Oct 15, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/70571
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed herein are non-endogenous, constitutively activated forms of the human 5-HT.sub.2A and human 5-HT.sub.2C receptors and uses of such receptors to screen candidate compounds. Further disclosed herein are candidate compounds identified by the screening method which act at the 5HT.sub.2A receptors. Yet further disclosed is a new class of compounds which act at the 5HT.sub.2A receptors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.