Human antibodies derived from immunized xenomice
US6150584A · kind A · utility
882Cited by
6References
12Claims
0Family size
Assignee
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Key dates
| Filing date | Oct 2, 1996 |
| Grant date | Nov 21, 2000 |
| Priority date | — |
| Expiry date | Oct 2, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/24
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Fully human antibodies against a specific antigen can be prepared by administering the antigen to a transgenic animal which has been modified to produce such antibodies in response to antigenic challenge, but whose endogenous loci have been disabled. Various subsequent manipulations can be performed to obtain either antibodies per se or analogs thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.