1,3,4-thiadiazoles and 1,3,4-Oxadiazoles as .alpha..sub.v .beta..sub.3 antagonists
US6153628A · kind A · utility
25Cited by
2References
8Claims
0Family size
Assignee
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Key dates
| Filing date | Nov 25, 1998 |
| Grant date | Nov 28, 2000 |
| Priority date | — |
| Expiry date | Nov 25, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to 1,3,4-thiadiazoles and 1,3,4-Oxadiazoles of Formula (I) which are useful as antagonists of .alpha..sub.v .beta..sub.3 and related integrin receptors, to pharmaceutical compositions containing such compounds, alone or in combination with other therapeutic agents, for the inhibition of cell adhesion and the tretment of angioginic disorders, inflammation, bone degradation, tumors, metastases, thrombosis, and other cell aggregation-related conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.