Phenylpyridyl compounds for inhibiting phosphodiesterase IV and methods of using same
US6153630A · kind A · utility
7Cited by
88References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 13, 1997 |
| Grant date | Nov 28, 2000 |
| Priority date | — |
| Expiry date | Nov 13, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel compounds which are effective PDE IV inhibitors are disclosed. The compounds possess improved PDE IV inhibition as compared to theophylline or rolipram as well as with improved selectivity with regard to PDE III inhibition. In certain aspects of the invention, the compounds also demonstrate PDE V inhibition. Pharmaceutical compositions containing the same and methods of treatment are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.