Isolated nuclear matrix targeting peptide

US6153729A · kind A · utility

Assignees

• St. Jude Children's Research Hospital, Inc. · US
• University of Massachusetts · US

Inventors

• Gary S. Stein · Shrewsbury, US
• Andre J. van Wijnen · Rochester, US
• Janet L. Stein · Shrewsbury, US
• Jane B. Lian · Westborough, US
• Jeanne B. Lawrence · Mapleville, US
• Cong-Mei Zeng · Topsfield, US
• Lindsay Shopland · Hopkinton, US
• Scott Hiebert · Moorestown, US
• Shari Meyers · Shreveport, US
• Sheldon Penman · Brookline, US

Key dates

• Filing date: Jun 19, 1998
• Grant date: Nov 28, 2000
• Expiry date: Jun 19, 2018

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Nuclear matrix targeting peptides (NMTPs) capable of delivering a variety of therapeutic and diagnostic agents, such as transcription regulatory factors, to the nuclear matrix of a cell are disclosed.