Implanted tumor cells for the prevention and treatment of cancer
US6156305A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 5, 1995 |
| Grant date | Dec 5, 2000 |
| Priority date | — |
| Expiry date | Jun 5, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/5152
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method to prevent or treat cancer in a patient comprising: administering a first set of tumor cells; where at least some of the first tumor cells have at least one tumor antigen corresponding to antigen of the patient's tumor cells; where the tumor cells are contained in an implantable chamber; the chamber defined by a wall including a porous boundary between the patient's immune cells and the contained cells and pervious to subcellular antigenic material; where the boundary prevents contact between patient immune cells and the contained tumor cells, and where the boundary permits subcellular antigenic materials to exit the chamber; and rendering a second set of tumor cells nontumorigenic; where at least some of the second tumor cells have at least one tumor antigen corresponding to antigen of the patient's tumor cells; administering the second tumor cells to the patient without containing them in a chamber.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.