Mammalian IAP gene family, primers, probes, and detection methods
US6156535A · kind A · utility
11Cited by
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15Claims
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Key dates
| Filing date | Dec 22, 1995 |
| Grant date | Dec 5, 2000 |
| Priority date | — |
| Expiry date | Dec 22, 2015 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2510/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed is substantially pure DNA encoding mammalian IAP polypeptides; substantially pure polypeptides; and methods of using such DNA to express the IAP polypeptides in cells and animals to inhibit apoptosis. Also disclosed are conserved regions characteristic of the IAP family and primers and probes for the identification and isolation of additional IAP genes. In addition, methods for treating diseases and disorders involving apoptosis are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.