Process for the preparation of halogenated phenylmaloates

US6156925A · kind A · utility

Assignee

• American Cyanamid Company · US

Inventors

• Oliver Meyer · Ingelheim am Rhein, DE
• Rudi Eisenacht · Mainz, DE

Key dates

• Filing date: Sep 24, 1999
• Grant date: Dec 5, 2000
• Expiry date: Sep 24, 2019

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C67/343
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process for the preparation of dialkyl phenylmalonates of formula I, ##STR1## wherein R, R.sup.1, L.sup.1 and L.sup.2 have the meaning given in the claims which comprises treating an phenylbromide of formula II ##STR2## with a dialkyl malonate of formula III ##STR3## in an inert solvent in the presence of a base and a copper salt, wherein 1.0 mole of the phenylbromide of formula II is treated with the enolate obtained from 2.0 to 4.0 moles of the dialkyl malonate of formula III and 2.0 to 3.8 moles of the base.