Dentifrice products and methods for remineralizing and/or mineralizing teeth
US6159449A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 3, 1997 |
| Grant date | Dec 12, 2000 |
| Priority date | — |
| Expiry date | Apr 3, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2800/88
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A dentifrice product substantially free of water-soluble inorganic orthophosphates and capable of remineralizing subsurface lesions and/or mineralizing exposed dentinal tubules in teeth, contains (A) a discrete cationic part containing at least one water-soluble and/or partially water-soluble calcium compound and a fluoride-protecting amount of at least one water-soluble and/or partially water-soluble magnesium compound, and (B) a discrete anionic part containing at least one water-soluble fluoride compound. The cationic and anionic parts are disposed separate from one another in the product and are simultaneously releasable from the product. The cationic and anionic parts each have a pH in water such that a mixed aqueous composition formed by mixing the cationic and anionic parts with (i) saliva or (ii) water and saliva has a pH of from about 4.0 to about 10.0. The mixed aqueous composition simultaneously applies the cationic and anionic parts to the tooth surfaces being treated. Dentifrice products containing a minor amount of at least one water-soluble inorganic orthophosphate compound in the anionic part and dentifrice products which are substantially devoid of water-soluble in…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.