Composition containing an acid-labile benzimidazole and process for its preparation
US6159499A · kind A · utility
23Cited by
20References
20Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Oct 20, 1998 |
| Grant date | Dec 12, 2000 |
| Priority date | — |
| Expiry date | Oct 20, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P1/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a composition, particularly adapted to oral administration, substantially free of alkaline-reacting compounds. The composition comprises (a) a core containing an acid-labile benzimidazole active principle, where the core comprises a plurality of nuclei and the active principle mixed together and then compressed together, and where the active principle is not in the form of an alkaline salt; (b) an intermediate layer; and (c) an enteric layer; provided that omeprazole is not the benzimidazole active principle. A process for preparing the composition is also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.