Coating having biological activity and medical implant having surface carrying the same and method
US6159531A · kind A · utility
108Cited by
5References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 30, 1999 |
| Grant date | Dec 12, 2000 |
| Priority date | — |
| Expiry date | Aug 30, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L33/0088
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A multi-step method for surface modification of a medical device having at least one surface exposed to tissue and/or blood. The steps comprise a low temperature plasma treatment of the said surface to provide a plasma deposited layer having functional groups. A chemical treatment of the plasma deposited layer using multifunctional linkers establishes covalent bonds with the plasma deposited layer. A bioactive/biocompatible agent react with the multifunctional linkers so that molecules thereof are covalently bound to said surface.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.