Solid phase immunoassay to detect inhibitors of proteolytic enzymes
US6159746A · kind A · utility
2Cited by
3References
6Claims
0Family size
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Key dates
| Filing date | Sep 23, 1996 |
| Grant date | Dec 12, 2000 |
| Priority date | — |
| Expiry date | Sep 23, 2016 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/839
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Solid phase immunoassay for detecting specific inhibitors of proteolytic enzymes in biological fluids, which comprises: a) contacting a tubulin peptide covalently linked to a support with a solution containing a proteolytic activity together with a protease inhibitor, b) detecting the inhibitor activity against the selected proteases by contacting the support with a solution containing a labelled monoclonal antibody which specifically recognises the free end of the tubulin peptide linked to the support.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.