Anti-RAS intracellular binding proteins and use thereof
US6159947A · kind A · utility
8Cited by
1References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 28, 1995 |
| Grant date | Dec 12, 2000 |
| Priority date | — |
| Expiry date | Dec 28, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to nucleic acid sequences encoding intracellular binding proteins. More particularly, the nucleic acid comprises a gene coding for an intracellular single chain antibody specific for a ras oncogene under the control of a promoter, the antibody is functional in mammalian cells, and inhibits the transformation of cells that express a ras oncogene.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.