Sensor histidine kinase of streptococcus pneumoniae

US6162619A · kind A · utility

Assignees

• SmithKline Beecham Limited · US
• SmithKline Beeacham P.L.C. · GB

Inventors

• Sanjoy Biswas · Paoli, US
• Alexander Bryant · Chester Springs, US
• Yigong Ge · Mill Valley, US
• David John Holmes · West Chester, US
• Karen Anne Ingraham · Auburn, US
• Deborah Dee Jaworski · West Chester, US
• Andrea Marra · New Haven, US
• Lisa Kathleen Shilling · Newtown, US
• John P. Throup · New Hope, US
• Min Wang · Blue Bell, US
• Nicola Gail Wallis · Wayne, US
• Magdalena Zalacain · West Chester, US

Key dates

• Filing date: May 20, 1998
• Grant date: Dec 19, 2000
• Expiry date: May 20, 2018

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N9/1205
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The invention provides Histidine kinase polypeptides and polynucleotides encoding Histidine kinase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing Histidine kinase polypeptides to screen for antibacterial compounds.