Fermentation process for preparing erythritol using mutant cells by controlling osmotic pressure
US6162636A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 27, 1999 |
| Grant date | Dec 19, 2000 |
| Priority date | — |
| Expiry date | Aug 27, 2019 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/911
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to a fermentation process for preparing erythritol with high productivity with novel mutant of Trigonopsis variabilis, more specifically, for preparing erythritol under optimal fermentation conditions for maximum erythritol production by optimizing the environmental conditions of culture such as pH, temperature and controlling osmotic pressure. A two-stage fermentation was performed to control osmotic pressure. Osmotic pressure was adjusted to a low level during growth phase and to a high level during production phase by adding glucose and NaCl. Therefore, erythritol production could be increased due to the increased mutant cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.