Method for transferring genes to the heart using AAV vectors
US6162796A · kind A · utility
14Cited by
4References
36Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 27, 1995 |
| Grant date | Dec 19, 2000 |
| Priority date | — |
| Expiry date | Sep 27, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2750/14143
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to the use of adeno-associated virus vectors for the transfer of genes to the heart and vasculature. The vector preferably contains a gene encoding a protein which improves heart and vascular function during heart failure. In a specific embodiment, the vector is introduced into the heart and vasculature via a catheter, with the aid of fluoroscopy. The method and vectors for use therein provide for safe and stable gene expression of the transferred genes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.