Method for producing .alpha.-alkoxy-.alpha.-trifluoromethyl-aryl acetic esters and -aryl acetic acids

US6162943A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Norbert Lui · Odenthal, DE
• Albrecht Marhold · Leverkusen, DE

Key dates

• Filing date: Apr 16, 1999
• Grant date: Dec 19, 2000
• Expiry date: Apr 16, 2019

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C67/31
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Process for the preparation of .alpha.-alkoxy-.alpha.-trifluoromethyl-arylacetic esters of the formula (I) ##STR1## wherein R is a component selected from the group consisting of C.sub.1 -C.sub.6 -alkyl, C.sub.2 -C.sub.6 -alkenyl, C.sub.3 -C.sub.7 -cycloalkyl, C.sub.6 -C.sub.10 -aryl and C.sub.1 -C.sub.6 -halogenoalkyl, R' is selected from the group consisting of C.sub.1 -C.sub.4 -alkyl, X is selected from the group consisting of halogen, C.sub.1 -C.sub.4 -alkyl, C.sub.2 -C.sub.4 -alkenyl, C.sub.6 -C.sub.10 -aryl or C.sub.1 -C.sub.4 -alkoxy and nitro, and n is zero or an integer from 1 to 3.