Patent · US Expired

Method and apparatus for in situ formation of hydrogels

US6165201A · kind A · utility

414Cited by
36References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 3, 1999
Grant dateDec 26, 2000
Priority date
Expiry dateSep 3, 2019

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61M25/0071
  • WIPO fieldMedical technology
  • WIPO sectorInstruments

Abstract

Methods and apparatus of forming in situ tissue adherent barriers are provided using a sprayer capable of applying two or more viscous crosslinkable solutions to tissue. The sprayer comprises separate spray nozzles for each of two or more crosslinkable solutions, wherein each nozzle is either surrounded by an annular gas flow outlet or in communication with a gas-pressurized chamber, and also may include valves that prevent backflow through the supply lines carrying the crosslinkable solutions, and a venting system for venting excess pressure for laparoscopic applications In the presence of gas flow, the crosslinkable solutions are atomized and mixed to form a spray. Multi-component hydrogel systems suitable for use with the inventive methods and apparatus are also described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.