Patent · US Expired

Methods of transcriptionally modulating expression of viral genes and genes useful for production of proteins

US6165712A · kind A · utility

115Cited by
22References
23Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 5, 1995
Grant dateDec 26, 2000
Priority date
Expiry dateJun 5, 2015

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02A50/30
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides a method of transcriptionally modulating the expression of a gene encoding a protein of interest, the expression of which gene is associated with the production in cell culture of a protein encoded by the gene, which comprises contacting a cell, which is capable of expressing the gene, with an amount of a molecule effective to transcriptionally modulate expression of the gene and thereby affect the level of the protein encoded by the gene which is expressed by the cell in culture, which molecule (a) directly transcriptionally modulates expression of the gene.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.