DNA fragmentation factor involved in apoptosis
US6165737A · kind A · utility
26Cited by
1References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 16, 1998 |
| Grant date | Dec 26, 2000 |
| Priority date | — |
| Expiry date | Apr 16, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/4747
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention provides methods and compositions relating to DNA Fragmentation Factor (DFF) polypeptides and related nucleic acids. More particularly, the present invention provides the sequence for the active subunit of DFF. The polylpeptides may be produced recombinantly from host cells transformed from the disclosed DFF encoding nucleic acids or purified from human cells. The invention provides isolated DFF hybridization probes and primers capable of specifically hybridization with the disclosed DFF genes, DFF-specific binding agents such as specific antibodies, and methods of making and using the subject compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.