Parainfluenza virus glycoproteins and vaccines
US6165774A · kind A · utility
3Cited by
2References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 8, 1998 |
| Grant date | Dec 26, 2000 |
| Priority date | — |
| Expiry date | Aug 8, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2760/18734
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
In summary of this disclosure, the present invention provides hemagglutinin-neuraminidase (HN) and Fusion (F) glycoproteins isolated and purified from parainfluenza viruses types 1, 2 and 3, methods of producing the same, and uses thereof in immunogenic compositions and diagnostic embodiments. In particular, a trivalent vaccine containing HN and F glycoproteins from PIV-1, PIV-2 and PIV-3 generated an immune response capable of neutralizing each of the virus types. Modifications are possible within the scope of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.