3,4-diamino-3-cyclobutene-1,2-dione derivatives which inhibit leukocyte adhesion mediated by VLA-4
US6166050A · kind A · utility
27Cited by
1References
39Claims
0Family size
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Key dates
| Filing date | Dec 10, 1999 |
| Grant date | Dec 26, 2000 |
| Priority date | — |
| Expiry date | Dec 10, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of the formula ##STR1## which inhibit leukocyte adhesion mediated by interaction of the .alpha..sub.4 .beta..sub.1 integrin (VLA-4) with its counterreceptor VCAM-1, and their use for the treatment of inflammatory and autoimmune diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.