Process for making a bioprosthetic device
US6166184A · kind A · utility
112Cited by
20References
42Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 18, 1997 |
| Grant date | Dec 26, 2000 |
| Priority date | — |
| Expiry date | Aug 18, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08H1/06
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Methods for making bioprosthetic devices made of collagen-based material having collagen amine groups and collagen carboxyl groups are provided. The methods include blocking at least a portion of the collagen amine groups with a blocking agent, activating at least a portion of the collagen carboxyl groups after blocking at least a portion of the collagen amine groups to form activated carboxyl groups, and contacting the activated collagen carboxyl groups with a polyfunctional spacer to crosslink the collagen-based material.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.