Monoclonal antibody which binds to a human-Th2-specific protein and hybridoma
US6166186A · kind A · utility
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Key dates
| Filing date | Jan 10, 2000 |
| Grant date | Dec 26, 2000 |
| Priority date | — |
| Expiry date | Jan 10, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present specification provides a means for specifying the condition and type of immune-related diseases on the basis of knowledge about the polarization of the distribution of helper T-cell subsets Th1 and Th2. More specifically, the gene (B19), specific only to the human Th2, is prepared by a subtraction method. A human-Th2-specific protein which the gene encodes is produced by recombinant methods, and a monoclonal antibody against the Th2-specific protein and a hybridoma which produces the monoclonal antibody is provided.
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