GPIIb/IIIa platelet receptors assay
US6168925A · kind A · utility
2Cited by
5References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 8, 1999 |
| Grant date | Jan 2, 2001 |
| Priority date | — |
| Expiry date | Feb 8, 2019 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/75
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to a method of determining, on a test sample, the occupation of the cellular GPIIb/IIIa receptor by an antagonist of fibrinogen, characterized in that the number of receptors occupied is determined in the said sample with the aid of an antibody MAb1 which is a competitor for the antagonist, and the total number of occupied or unoccupied receptors is determined with the aid of a so-called noncompetitor antibody MAb2 specific for the occupied or unoccupied receptor and the rate of occupation of the GPIIb/IIIa receptors in the sample is deduced therefrom.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.