Methods for releasing a ligand from a complex
US6171801A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 17, 1997 |
| Grant date | Jan 9, 2001 |
| Priority date | — |
| Expiry date | Jul 17, 2017 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/25375
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
One aspect of the present invention relates to a method for releasing a ligand from a complex thereof. The method comprises contacting a medium suspected of containing such complex with an effective amount of a compound effective in releasing the ligand. Another aspect of the present invention is an improvement in a method for the determination of an analyte that is a member of a specific binding pair in a sample suspected of containing such analyte. The method comprises the steps of (a) providing in an assay medium the sample and a binding partner for the analyte and (b) detecting the binding of the binding partner to the analyte. The improvement comprises including in the assay medium a compound of the invention in an amount sufficient to enhance the accuracy of the determination. The invention has particular application to a method for releasing mycophenolic acid from a complex thereof. The method provides an improvement in a method for the determination of mycophenolic acid in a sample suspected of containing mycophenolic acid. The present invention also provides assay reagents as well as packaged kits useful for performing the methods of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.