Phospholipid derivatives

US6172050A · kind A · utility

Assignee

• Asta Medica Aktiengesellschaft · DE

Inventors

• Gerhard Nossner · Feucht, DE
• Bernhard Kutscher · Maintal, DE
• Jurgen Engel · Alzenau, DE
• Wolfgang Schumacher · Langen, DE
• Jurij Stekar · Bielefeld, DE
• Peter Hilgard · Frankfurt, DE

Key dates

• Filing date: Aug 4, 1997
• Grant date: Jan 9, 2001
• Expiry date: Aug 4, 2017

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Phospholipid derivatives of Formula X: ##STR1## wherein A is the ring system ##STR2## in which R is a linear or branched alkyl radical having 10 to 24 carbon atoms which may contain one or more double or triple bonds; R1 and R2 are independently hydrogen or linear alkyl radicals having 1 to 3 carbon atoms; y is 0, 1, 2 or 3; m and n are independently 0 or in an integer, with the proviso that m+n is between 2 and 8; or A is a tropanio or quinuclidinio ring system, which is linked via a carbon-carbon bond and is optionally substituted by one or more methyl groups; processes for the preparation of the derivatives, and methods for treating tumors therewith.