Patent · US Expired

Inhibitors of prenyl-protein transferase

US6172076A · kind A · utility

34Cited by
6References
19Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 14, 1999
Grant dateJan 9, 2001
Priority date
Expiry dateJun 14, 2019

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D513/10
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention is directed to conformationally constrained compounds which inhibit prenyl-protein transferase and the prenylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting prenyl-protein transferase and the prenylation of the oncogene protein Ras.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.