1,5-dihydro-pyrazolo[34-D]-pyrimidinone derivatives

US6174884A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Helmut Haning · Milford, US
• Ulrich Niewohner · Wermelskirchen, DE
• Ulrich Rosentreter · Binnen, DE
• Thomas Schenke · Odenthal, DE
• Jörg Keldenich · Wuppertal, DE
• Erwin Bischoff · Wuppertal, DE
• Karl-Heinz Schlemmer · Wuppertal, DE
• Helmuth Schutz · Regensburg, DE
• Gunter Thomas · Arese, IT

Key dates

• Filing date: Aug 16, 1999
• Grant date: Jan 16, 2001
• Expiry date: Aug 16, 2019

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P15/10
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The 1,5-dihydro-pyrazolo[3,4-d]-pyrimidinone derivatives are prepared by fusing the pyrimidone heterocycle with the suitably substituted pyrazoles. The compounds are suitable as active compounds in medicaments, in particular in medicaments for the treatment of cardiovascular and cerebrovascular diseases, diseases of the peripheral blood vessels and diseases of the urogenital tract.