Polypeptides encoded by Kaposi sarcoma-associated herpes virus the use thereof in diagnosis and therapy

US6177080A · kind A · utility

Assignee

• Biotest AG · DE

Inventors

• Bernhard Fleckenstein · Wiesenthau, DE
• Jens-Christian Albrecht · Ergolding, DE
• Frank Neipel · Erlangen, DE
• Dieter Lang · Velbert, DE

Key dates

• Filing date: Jul 8, 1998
• Grant date: Jan 23, 2001
• Expiry date: Jul 8, 2018

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2710/16422
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to polypeptides of the Kaposi sarcoma-associated herpes virus which have a part-sequence of at least 10 consecutive amino acids from the sequence Met Ser Ser Thr Gln Ile Arg Thr Glu Ile Pro Val Ala Leu Leu Ile Leu Cys Leu Cys Leu Val Ala Cys His Ala Asn Cys Pro Thr Tyr Arg Ser His Leu Gly Phe Trp Gln Glu Gly Trp Ser Gly Gln Val Tyr Gln Asp Trp Leu Gly Arg Met Asn Cys Ser Tyr Glu Asn Met Thr Ala Leu Glu Ala Val Ser Leu Asn Gly Thr Arg Leu Ala Ala Gly Ser Pro Ser Ser Glu Tyr Pro Asn Val Ser Val Ser Val Glu Asp Thr Ser Ala Ser Gly Ser Gly Glu Asp Ala Ile Asp Glu Ser Gly Ser Gly Glu Glu Glu Arg Pro Val Thr Ser His Val Thr Phe Met Thr Gln Ser Val Gln Ala Thr Thr Glu Leu Thr Asp Ala Leu Ile Ser Ala Phe Ser Gly Val Leu His Val Ser Thr Val Ile Pro Arg Asn Trp Val Asn Arg Arg Cys Val Gly Ile Lys Arg Asn Leu Thr Phe Cys Leu Ile Tyr Arg Ile Ile Phe Ile Trp Gly Thr Ile Gln Asp His Ala Asn Ser Arg Ile Thr Gly Arg Arg Lys Arg Gln Lys and to the use thereof in therapy and diagnosis.