Processes to generate submicron particles of water-insoluble compounds
US6177103A · kind A · utility
57Cited by
2References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 18, 1999 |
| Grant date | Jan 23, 2001 |
| Priority date | — |
| Expiry date | Jun 18, 2019 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S977/906
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Submicron particles of water-insoluble compounds, particularly drugs, are prepared by simultaneously stabilizing microparticulate suspensions of same with surface modifier molecules by rapid expansion into an aqueous medium from a compressed solution of the compound and surface modifiers in a liquefied gas and optionally homogenizing the aqueous suspension thus formed with a high pressure homogenizer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.