Patent · US Expired

Method for the fermentative production of D-pantothenic acid using Coryneform bacteria

US6177264A · kind A · utility

31Cited by

0References

25Claims

0Family size

Assignees

Degussa-Huels AG · DE
Forschungszentrum Jülich GmbH · DE

Inventors

Lothar Eggeling · Jülich, DE
Georg Thierbach · Bielefeld, DE
Hermann Sahm · Jülich, DE

Key dates

Filing date	May 26, 1999
Grant date	Jan 23, 2001
Priority date	—
Expiry date	May 26, 2019

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12P13/02
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The invention discloses three polynucleotide sequences for the fermentative production of D-pantothenic acid. These polynucleotide sequences are genes named panB, encoding a ketopantoate hydroxymethyltransferase, panC, encoding pantothenate synthase, and ilvD, encoding dihydroxy-acid dehydratase. The genes panB and panC are found on the same operon, panBC, while the gene ilvD is found in a separate operon. These genes can be used separately or together to enhance the production of D-pantothenic acid in microorganisms, especially in Corynebacterium.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.