4,5,6,7-tetrahydro-thieno[3, 2-C]pyridine derivatives, their preparation and use
US6177443A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 5, 1998 |
| Grant date | Jan 23, 2001 |
| Priority date | — |
| Expiry date | Mar 5, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/47
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to pharmaceutical compositions comprising a pharmaceutically acceptable carrier or diluent and a compound of formula I ##STR1## wherein A together with the double bond of formula I is benzene or thiophene; R.sup.1 is optionally substituted C.sub.1-6 alkyl or optionally substituted aryl; R.sup.2 is optionally substituted C.sub.1-6 -alkyl, optionally substituted aralkyl, or --COR.sup.3, wherein R.sup.3 is optionally substituted C.sub.1-6 -alkyl, optionally substituted aralkyl, or optionally substituted aryl; R.sup.4 and R.sup.5 independently are hydrogen, halogen, perhalomethyl, optionally substituted C.sub.1-6 -alkyl, hydroxy, optionally substituted C.sub.1-6 -alkoxy, nitro, cyano, amino, optionally substituted mono- or optionally substituted di-C.sub.1-6 -alkylamino, acylamino, C.sub.1-6 -alkoxycarbonyl, carboxy or carbamoyl; n is 0, and m is 1, and methods of treating or preventing a disease of the endocrinologic system.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.