Blocked functional reagants for cross-linking biological tissues
US6177514A · kind A · utility
173Cited by
3References
35Claims
0Family size
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Key dates
| Filing date | Apr 9, 1999 |
| Grant date | Jan 23, 2001 |
| Priority date | — |
| Expiry date | Apr 9, 2019 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S623/915
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A method for cross-linking biological tissue is provided which uses as a cross-linking agent a low molecular weight, substantially monomeric polyfunctional aldehyde formed in situ or just prior to cross-linking. The polyfunctional aldehyde is essentially free of the undesirable heterogeneous polymeric species that result from polyfunctional aldehyde self-reactivity. Also provided is biological tissue that is cross-linked with a substantially monomeric glutaraldehyde.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.